Janos Honkonen's recommendation list of independent science fiction films blew up after it was posted to Reddit over the weekend. There's great discussion and even better movie suggestions in the Reddit thread about the post.
I haven't seen any of the indie films Janos recommends except for Trollhunter, which was incredible (and still on Netflix right now, I think). Gattaca, one of his big-budget recommendations, is one of my all-time faves though, and you really, REALLY should watch it.
Got any suggestions for me?